Monday, September 23rd, 6 pm
***Union Station, Northampton***
“Imprinting, X-inactivation, and Epigenetics – how your DNA remembers history.”
What is epigenetics (besides the latest sciency buzz word) and why should we care?
What is genome imprinting (nothing to do with baby ducks)
Why are all female mammals mosaic (yes, 1/2 of you reading this)?
How what your grandmother ate may influence how you use your DNA (always listen to your grandma)
What does this all have to do with stem cells, reprogramming and the fountain of youth?
Prof. Jesse Mager performed his doctoral work at UNC Chapel Hill graduating with a PhD in Genetics. He then continued with short postdoctoral training stints at MIT and UPenn before starting his own research group at the University of Massachusetts in 2004, where he has recently been promoted to full professor. Prof. Mager’s research interests lie in understanding epigenetic regulation of mammalian genomes using the earliest stages of mouse development as a model to understand humans. Although brief in time, early development is an extremely dynamic period during which the very first cell fate decisions are made. These key biological processes require global, yet exquisitely precise chromatin remodeling in order to properly regulate gene expression and allow successful development into complex organisms with a wide variety of tissue and cell functions.
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